Diisopropylethylamine → 8-[3-(4-Cyano-tetrahydro-pyran-4-yl)-phenylsulfanyl]-5-phenyl-imidazo[1,2-a]quinoline-2-carboxylic acid ethyl ester

반응식

[CH2:1]([O:3][C:4]([C:6]1[N:7]=[C:8]2[CH:17]=[C:16]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[C:15]3[C:10](=[CH:11][C:12](I)=[CH:13][CH:14]=3)[N:9]2[CH:25]=1)=[O:5])[CH3:2].[SH:26][C:27]1[CH:28]=[C:29]([C:33]2([C:39]#[N:40])[CH2:38][CH2:37][O:36][CH2:35][CH2:34]2)[CH:30]=[CH:31][CH:32]=1.C1(P(C2C=CC=CC=2)C2C3OC4C(=CC=CC=4P(C4C=CC=CC=4)C4C=CC=CC=4)C(C)(C)C=3C=CC=2)C=CC=CC=1.CCN(C(C)C)C(C)C>O1CCOCC1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd]>[CH2:1]([O:3][C:4]([C:6]1[N:7]=[C:8]2[CH:17]=[C:16]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[C:15]3[C:10](=[CH:11][C:12]([S:26][C:27]4[CH:32]=[CH:31][CH:30]=[C:29]([C:33]5([C:39]#[N:40])[CH2:34][CH2:35][O:36][CH2:37][CH2:38]5)[CH:28]=4)=[CH:13][CH:14]=3)[N:9]2[CH:25]=1)=[O:5])[CH3:2]