N-bromobutanimide → Ethyl 2-(bromomethyl)-4-fluorobenzoate

HRID 2082856

반응식

HRID 2082856 반응식
[F:1][C:2]1[CH:7]=[C:6]([CH3:8])[C:5]([C:9]([O:11][CH2:12][CH3:13])=[O:10])=[CH:4][CH:3]=1.[Br:14]N1C(=O)CCC1=O>>[Br:14][CH2:8][C:6]1[C:5]([C:9]([O:11][CH2:12][CH3:13])=[O:10])=[CH:4][CH:3]=[C:2]([F:1])[CH:7]=1

참가 물질

3

반응물 2

HCID 67184N-bromobutanimideHCID 18920184Benzoic acid, 4-fluoro-2-methyl-, ethyl ester

생성물 1

HCID 12893417Ethyl 2-(bromomethyl)-4-fluorobenzoate

실험 절차

Reaction of ethyl 5-fluoro-o-toluate with N-bromosuccinimide as described in Example 1a provides ethyl α-bromo-5-fluoro-o-toluate as an oil.

출처 및 근거

ORD 기록
ord-1c3e8c02a01e497e86a0132f3477fe34
출처 데이터셋
uspto-grants-1978_04
특허 번호
US04082850

연결된 노트

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