Aluminum(III) Chloride → 2-Ethyl-2-n-propyl-5-hydroxy-6,7-dichloro-1-indanone

HRID 2083450노트

반응식

HRID 2083450 반응식
[CH2:1]([C:3]1([CH2:17][CH2:18][CH3:19])[CH2:11][C:10]2[C:5](=[C:6]([Cl:15])[C:7]([Cl:14])=[C:8]([O:12]C)[CH:9]=2)[C:4]1=[O:16])[CH3:2].[Cl-].[Al+3].[Cl-].[Cl-]>CCCCCCC>[CH2:1]([C:3]1([CH2:17][CH2:18][CH3:19])[CH2:11][C:10]2[C:5](=[C:6]([Cl:15])[C:7]([Cl:14])=[C:8]([OH:12])[CH:9]=2)[C:4]1=[O:16])[CH3:2]

참가 물질

4

반응물 2

HCID 6451240Aluminum(III) ChlorideHCID 123955632-Ethyl-2-n-propyl-5-methoxy-6,7-dichloro-1-indanone

생성물 1

HCID 123955852-Ethyl-2-n-propyl-5-hydroxy-6,7-dichloro-1-indanone

시약·촉매·용매 1

HCID 8900Heptane용매

실험 절차

2-Ethyl-2-n-propyl-5-hydroxy-6,7-dichloro-1-indanone is prepared following substantially the same procedure described in Example 5, Step F, using the following substances: 2-ethyl-2-n-propyl-5-methoxy-6,7-dichloro-1-indanone (11 g., .037 mole), aluminum chloride (12.5 g., 0.094 mole) and heptane (400 ml.). The above procedure gives 9.0 g. of 2-ethyl-2-n-propyl-5-hydroxy-6,7-dichloro-1-indanone which after recrystallization from methylcyclohexane melts at 153° C.

후처리

  1. customThe above procedure gives 9.0 g
  2. customof 2-ethyl-2-n-propyl-5-hydroxy-6,7-dichloro-1-indanone which after recrystallization from methylcyclohexane melts at 153° C.

출처 및 근거

ORD 기록
ord-28c1086691214403b992f4ac7a8c6258
출처 데이터셋
uspto-grants-1978_04
특허 번호
US04085219

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