Pyrrolidine → HCID 178479348, 화합물

HRID 2083961노트

반응식

C(OC([NH:11][C@H:12]([C:20]([OH:22])=O)[CH2:13][CH2:14][CH2:15][NH:16][C:17](=[NH:19])[NH2:18])=O)C1C=CC=CC=1.[CH:23]1([S:29]([Cl:32])(=[O:31])=[O:30])[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1.[NH:33]1[CH2:37][CH2:36][CH2:35][CH2:34]1>>[ClH:32].[NH:19]=[C:17]([NH:18][S:29]([CH:23]1[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1)(=[O:31])=[O:30])[NH:16][CH2:15][CH2:14][CH2:13][C@@H:12]([C:20]([N:33]1[CH2:37][CH2:36][CH2:35][CH2:34]1)=[O:22])[NH2:11]

참가 물질

반응물 3

HCID 31268Pyrrolidine

HCID 237554Cyclohexanesulfonyl chloride

HCID 178512917HCID 178512917, 화합물

생성물 1

HCID 178479348HCID 178479348, 화합물

실험 절차

Starting from (S)-N2-(benzyloxycarbonyl)-arginine, cyclohexanesulphonyl chloride and pyrrolidine, the expected product is obtained according to the procedure described in Example 1.

출처 및 근거

ORD 기록: ord-5e4b59d79f574db7bff55ee92b9a0d27
출처 데이터셋: uspto-grants-2004_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06716843B2

반응 노트

불러오는 중…