Pyridine → 5,5-Dimethyl-3-oxocyclohex-1-en-1-yl acetate
반응식
[C:1](Cl)(=[O:3])[CH3:2].[CH3:5][C:6]1([CH3:14])[CH2:11][C:10](=[O:12])[CH2:9][C:8](=[O:13])[CH2:7]1.N1C=CC=CC=1>C(Cl)(Cl)Cl>[C:1]([O:12][C:10]1[CH2:11][C:6]([CH3:14])([CH3:5])[CH2:7][C:8](=[O:13])[CH:9]=1)(=[O:3])[CH3:2]참가 물질
5
실험 절차
Acetyl chloride (1.1 ml, 15.65 mmol) was added to a stirred solution of 5,5-dimethyl-cyclohexane-1,3-dione (2.1 g, 14.23 mmol) and pyridine (1.14 ml), in chloroform (50 ml). The mixture was stirred at room temperature for about 1.5 hours, then washed with water, 0.1N HCl, saturated aqueous sodium hydrogen carbonate and water. The organic phase was dried over sodium sulfate and evaporated to dryness to give 2.5 g (96%) of the title compound as a colourless oil, which was used as such without any further purification.
후처리
- washwashed with water, 0.1N HCl, saturated aqueous sodium hydrogen carbonate and water
- dry with materialThe organic phase was dried over sodium sulfate
- customevaporated to dryness
출처 및 근거
- ORD 기록
- ord-efaf1dabc53c4df7a35d7d91a9f4ec50
- 출처 데이터셋
- uspto-grants-2004_04
- 특허 번호
- US06716856B1
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