4-Morpholinecarbonyl chloride → 2-(ethoxymethyl)-6,7-dimethyl-1-{2-[1-(morpholin-4-ylcarbonyl)piperidin-4-yl]ethyl}-1H-imidazo[4,5-c]pyridin-4-amine
반응식
[N:1]1([C:7](Cl)=[O:8])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[CH2:10]([O:12][CH2:13][C:14]1[N:15]([CH2:26][CH2:27][CH:28]2[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]2)[C:16]2[C:21]([CH3:22])=[C:20]([CH3:23])[N:19]=[C:18]([NH2:24])[C:17]=2[N:25]=1)[CH3:11]>>[CH2:10]([O:12][CH2:13][C:14]1[N:15]([CH2:26][CH2:27][CH:28]2[CH2:29][CH2:30][N:31]([C:7]([N:1]3[CH2:6][CH2:5][O:4][CH2:3][CH2:2]3)=[O:8])[CH2:32][CH2:33]2)[C:16]2[C:21]([CH3:22])=[C:20]([CH3:23])[N:19]=[C:18]([NH2:24])[C:17]=2[N:25]=1)[CH3:11]참가 물질
3
실험 절차
Using the method of Examples 5465, 4-morphlinecarbonyl chloride was reacted with 2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 445.2929.
출처 및 근거
- ORD 기록
- ord-e63cebd507c74483a5430f7b193fc87a
- 출처 데이터셋
- uspto-grants-2004_04