Phenol → N-(3-{1-[3-(4-Bromophenyl)-3-phenoxypropyl]-4-piperidinyl}phenyl)-2-methylpropanamide

HRID 2087291노트

반응식

HRID 2087291 반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([OH:29])[CH2:9][CH2:10][N:11]2[CH2:16][CH2:15][CH:14]([C:17]3[CH:18]=[C:19]([NH:23][C:24](=[O:28])[CH:25]([CH3:27])[CH3:26])[CH:20]=[CH:21][CH:22]=3)[CH2:13][CH2:12]2)=[CH:4][CH:3]=1.[C:30]1(O)[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]([O:29][C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[CH2:9][CH2:10][N:11]2[CH2:16][CH2:15][CH:14]([C:17]3[CH:18]=[C:19]([NH:23][C:24](=[O:28])[CH:25]([CH3:26])[CH3:27])[CH:20]=[CH:21][CH:22]=3)[CH2:13][CH2:12]2)=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 996PhenolHCID 22048618N-(3-{1-[3-(4-bromophenyl)-3-hydroxypropyl]-4-piperidinyl}phenyl)-2-methylpropanamide

생성물 1

HCID 22049099N-(3-{1-[3-(4-Bromophenyl)-3-phenoxypropyl]-4-piperidinyl}phenyl)-2-methylpropanamide

실험 절차

Prepared by Procedure A and Scheme AN using N-(3-{1-[3-(4-bromophenyl)-3-hydroxypropyl]-4-piperidinyl}phenyl)-2-methylpropanamide and phenol: ESMS m/e: 535.0 (M+H)+.

출처 및 근거

ORD 기록
ord-4458969fb7e14d45a346327928875dca
출처 데이터셋
uspto-grants-2004_04
특허 번호
US06727264B1

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