Hydrazine hydrate (1:1) → N-{3-[1-(6-Aminohexyl)4-piperidinyl]phenyl}-2-methylpropanamide

HRID 2087802

반응식

HRID 2087802 반응식
O=C1C2C(=CC=CC=2)C(=O)[N:3]1[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][N:18]1[CH2:23][CH2:22][CH:21]([C:24]2[CH:25]=[C:26]([NH:30][C:31](=[O:35])[CH:32]([CH3:34])[CH3:33])[CH:27]=[CH:28][CH:29]=2)[CH2:20][CH2:19]1.O.NN>>[NH2:3][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][N:18]1[CH2:23][CH2:22][CH:21]([C:24]2[CH:25]=[C:26]([NH:30][C:31](=[O:35])[CH:32]([CH3:33])[CH3:34])[CH:27]=[CH:28][CH:29]=2)[CH2:20][CH2:19]1

참가 물질

3

반응물 2

HCID 24654Hydrazine hydrate (1:1)HCID 16757364N-(3-{1-[6-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-YL)hexyl]-4-piperidinyl}phenyl)-2-methylpropanamide

생성물 1

HCID 16755868N-{3-[1-(6-Aminohexyl)4-piperidinyl]phenyl}-2-methylpropanamide

실험 절차

Prepared by Procedure AE and Scheme Y using N-(3-{1-[6-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)hexyl]-4-piperidinyl}phenyl)-2-methylpropanamide and hydrazine hydrate: ESMS m/e: 346.2 (M+H)+.

후처리

  1. customPrepared by Procedure AE and Scheme Y

출처 및 근거

ORD 기록
ord-decc669942d84f71b6eae10ba931bf70
출처 데이터셋
uspto-grants-2004_04
특허 번호
US06727264B1

연결된 노트

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