Triethylamine → 9H-Fluoren-9-yl 2-methylprop-2-enoate

HRID 2096097노트

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HRID 2096097 반응식
C(N(CC)CC)C.[C:8](Cl)(=[O:12])[C:9]([CH3:11])=[CH2:10].[OH:14][CH:15]1[C:27]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[C:21]2[C:16]1=[CH:17][CH:18]=[CH:19][CH:20]=2>C1(C)C=CC=CC=1>[C:8]([O:14][CH:15]1[C:27]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[C:21]2[C:16]1=[CH:17][CH:18]=[CH:19][CH:20]=2)(=[O:12])[C:9]([CH3:11])=[CH2:10]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 13528Methacryloyl chlorideHCID 74318Fluoren-9-ol

생성물 1

HCID 222368199H-Fluoren-9-yl 2-methylprop-2-enoate

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

With stirring and ice cooling, 111 g of triethylamine was added to a mixture of 120 g of methacrylic acid chloride, 182 g of 9-hydroxyfluorene, and 1500 g of toluene. The mixture was stirred at room temperature for 16 hours. By standard aqueous work-up and solvent distillation, a crude product was obtained. It was purified by column chromatography, yielding the target compound, 9-fluorenyl methacrylate.

후처리

  1. stirringThe mixture was stirred at room temperature for 16 hours
  2. distillationBy standard aqueous work-up and solvent distillation
  3. customa crude product was obtained
  4. customIt was purified by column chromatography

출처 및 근거

ORD 기록
ord-c7531710d85e458e9f5f60f69774a79e
출처 데이터셋
uspto-grants-2013_05
특허 번호
US08450042B2

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