4-Methoxyphenylacetic Acid → 2-(2-(4-Methoxyphenyl)acetamido)-4-methylthiophene-3-carboxamide

반응식

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]([OH:12])=O)=[CH:5][CH:4]=1.[NH2:13][C:14]1[S:15][CH:16]=[C:17]([CH3:22])[C:18]=1[C:19]([NH2:21])=[O:20]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:9][C:10]([NH:13][C:14]2[S:15][CH:16]=[C:17]([CH3:22])[C:18]=2[C:19]([NH2:21])=[O:20])=[O:12])=[CH:7][CH:8]=1

참가 물질

반응물 2

HCID 76904-Methoxyphenylacetic Acid

HCID 2938102-Amino-4-methylthiophene-3-carboxamide

생성물 1

HCID 687568372-(2-(4-Methoxyphenyl)acetamido)-4-methylthiophene-3-carboxamide

실험 절차

The title compound was prepared from 2-(4-methoxyphenyl)acetic acid (1.21 g, 7.22 mmol) and 2-amino-4-methylthiophene-3-carboxamide (1.12 g, 7.22 mmol) according to protocol B. Retention time (min)=1.903, method [1], MS (ESI) 305.0 (M+H).

출처 및 근거

ORD 기록: ord-b292648d2b1142a58ed9cc7740e14784
출처 데이터셋: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08450363B2

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