4-Methoxyphenylacetic Acid → N-(3-cyanothiophen-2-yl)-2-(4-methoxyphenyl)acetamide

HRID 2098154

반응식

HRID 2098154 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]([OH:12])=O)=[CH:5][CH:4]=1.[NH2:13][C:14]1[S:15][CH:16]=[CH:17][C:18]=1[C:19]#[N:20]>>[C:19]([C:18]1[CH:17]=[CH:16][S:15][C:14]=1[NH:13][C:10](=[O:12])[CH2:9][C:6]1[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=1)#[N:20]

참가 물질

3

반응물 2

HCID 76904-Methoxyphenylacetic AcidHCID 7366072-Aminothiophene-3-carbonitrile

생성물 1

HCID 2404093N-(3-cyanothiophen-2-yl)-2-(4-methoxyphenyl)acetamide

실험 절차

N-(3-cyanothiophen-2-yl)-2-(4-methoxyphenyl)acetamide was prepared from 2-(4-methoxyphenyl)acetic acid (1.37 g, 8.29 mmol) and 2-aminothiophene-3-carbonitrile (1.03 g, 8.29 mmol) according to protocol B. Retention time (min)=2.150, method [1], MS (ESI) 273.0 (M+H).

출처 및 근거

ORD 기록
ord-f0dd1448af164d6a98d36693b06f478f
출처 데이터셋
uspto-grants-2013_05
특허 번호
US08450363B2

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