Methyl bromoacetate → [8-Chloro-4-methyl-2-oxo-3-(4-pyrazol-1-ylbenzyl)-1,2-dihydroquinolin-5-yloxy]acetic acid methyl ester

반응식

[CH3:27][O:28][C:29]([CH2:30][Br:31])=[O:32].[Cl:1][c:2]1[cH:3][cH:4][c:5]([OH:26])[c:6]2[c:7]([CH3:25])[c:8]([CH2:13][c:14]3[cH:15][cH:16][c:17](-[n:20]4[n:21][cH:22][cH:23][cH:24]4)[cH:18][cH:19]3)[c:9](=[O:12])[nH:10][c:11]12>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([O:26][CH2:30][C:29]([O:28][CH3:27])=[O:32])[c:6]2[c:7]([CH3:25])[c:8]([CH2:13][c:14]3[cH:15][cH:16][c:17](-[n:20]4[n:21][cH:22][cH:23][cH:24]4)[cH:18][cH:19]3)[c:9](=[O:12])[nH:10][c:11]12

참가 물질

반응물 2

HCID 60984Methyl bromoacetate

HCID 674579118-chloro-5-hydroxy-4-methyl-3-(4-pyrazol-1-ylbenzyl)-1H-quinolin-2-one

생성물 1

HCID 67459078[8-Chloro-4-methyl-2-oxo-3-(4-pyrazol-1-ylbenzyl)-1,2-dihydroquinolin-5-yloxy]acetic acid methyl ester

출처 및 근거

ORD 기록: ord-68cf29aaa0cf43898034c94b40dc1a9c
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

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