N-bromobutanimide → 4-amino-7-bromo-2,3-dihydro-1H-isoindole-1,3-dione
반응식
[NH2:1][C:2]1[CH:12]=[CH:11][CH:10]=[C:4]2[C:5]([NH:7][C:8](=[O:9])[C:3]=12)=[O:6].[Br:13]N1C(=O)CCC1=O>CO>[NH2:1][C:2]1[CH:12]=[CH:11][C:10]([Br:13])=[C:4]2[C:5]([NH:7][C:8](=[O:9])[C:3]=12)=[O:6]참가 물질
4
실험 절차
3-Aminophthalimide (2.00 g, 12.3 mmol) was dissolved in methanol (200 mL), and the solution was added with N-bromosuccinimide (2.19 g, 12.3 mmol), followed by stirring at room temperature for 50 minutes. The obtained solid was collected by filtration and washed with methanol to obtain 3-amino-6-bromophthalimide (2.21 g, yield 74%).
후처리
- filtrationThe obtained solid was collected by filtration
- washwashed with methanol
출처 및 근거
- ORD 기록
- ord-71a5479c3a334ee98e9d5b229fda0e3e
- 출처 데이터셋
- uspto-grants-2010_06
- 특허 번호
- US07745641B2
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