Triethylamine → 3-Amino-4-phenyl-6-[1-(tert-butoxycarbonyl)-5-(4-methylpiperazin-1-ylsulfonyl)indol-2-yl]phthalimide

반응식

[NH2:1][C:2]1[C:12]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[CH:11][C:10](Br)=[C:4]2[C:5]([NH:7][C:8](=[O:9])[C:3]=12)=[O:6].[C:20]([O:24][C:25]([N:27]1[C:35]2[C:30](=[CH:31][C:32]([S:36]([N:39]3[CH2:44][CH2:43][N:42]([CH3:45])[CH2:41][CH2:40]3)(=[O:38])=[O:37])=[CH:33][CH:34]=2)[CH:29]=[C:28]1B(O)O)=[O:26])([CH3:23])([CH3:22])[CH3:21].CN1CCN(S(C2C=C3C(=CC=2)NC(B(O)O)=C3)(=O)=O)CC1.C1(C)C=CC=CC=1P(C1C=CC=CC=1C)C1C=CC=CC=1C.C(N(CC)CC)C>C(#N)C.C(OCC)(=O)C.CO.C([O-])(=O)C.[Pd+2].C([O-])(=O)C>[NH2:1][C:2]1[C:12]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[CH:11][C:10]([C:28]2[N:27]([C:25]([O:24][C:20]([CH3:23])([CH3:22])[CH3:21])=[O:26])[C:35]3[C:30]([CH:29]=2)=[CH:31][C:32]([S:36]([N:39]2[CH2:44][CH2:43][N:42]([CH3:45])[CH2:41][CH2:40]2)(=[O:37])=[O:38])=[CH:33][CH:34]=3)=[C:4]2[C:5]([NH:7][C:8](=[O:9])[C:3]=12)=[O:6]