Lithium Hydroxide → (+/-)-2-(4-(8-Fluoro-2-oxo-1,2-dihydroquinazolin-3 (4H)-yl)piperidine-1-carboxamido)-3-(7-methyl-1H-indazol-5-yl)propanoic Acid

반응식

[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[NH:10][C:9](=[O:12])[N:8]([CH:13]1[CH2:18][CH2:17][N:16]([C:19]([NH:21][CH:22]([CH2:27][C:28]3[CH:29]=[C:30]4[C:34](=[C:35]([CH3:37])[CH:36]=3)[NH:33][N:32]=[CH:31]4)[C:23]([O:25]C)=[O:24])=[O:20])[CH2:15][CH2:14]1)[CH2:7]2.O1CCCC1.CO.[OH-].[Li+]>O>[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[NH:10][C:9](=[O:12])[N:8]([CH:13]1[CH2:14][CH2:15][N:16]([C:19]([NH:21][CH:22]([CH2:27][C:28]3[CH:29]=[C:30]4[C:34](=[C:35]([CH3:37])[CH:36]=3)[NH:33][N:32]=[CH:31]4)[C:23]([OH:25])=[O:24])=[O:20])[CH2:17][CH2:18]1)[CH2:7]2