Cyclopentanol → HCID 57799782, 화합물

HRID 2100865노트

반응식

HRID 2100865 반응식
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[C:9]([O:12][CH3:13])[CH:10]=2)[CH:5]=[C:4]([NH:16][C:17]2[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=2)[N:3]=1.[CH:23]1([OH:28])[CH2:27][CH2:26][CH2:25][CH2:24]1>>[CH:23]1([O:28][C:2]2[C:11]3[C:6](=[CH:7][C:8]([O:14][CH3:15])=[C:9]([O:12][CH3:13])[CH:10]=3)[CH:5]=[C:4]([NH:16][C:17]3[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=3)[N:3]=2)[CH2:27][CH2:26][CH2:25][CH2:24]1

참가 물질

3

반응물 2

HCID 7298CyclopentanolHCID 57799766HCID 57799766, 화합물

생성물 1

HCID 57799782HCID 57799782, 화합물

실험 절차

Similar procedure as described in example 10 was used, starting from (1-chloro-6,7-dimethoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine and cyclopentanol to give (1-Cyclopentyloxy-6,7-dimethoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS m/e 369(MH+).

출처 및 근거

ORD 기록
ord-fc702c2a050c48c78bcd04c5aa94361d
출처 데이터셋
uspto-grants-2009_08
특허 번호
US07572809B2

반응 노트

불러오는 중…