Propanal → 3-[3-Methyl-8-(trifluoromethyl)quinolin-4-yl]phenol

반응식

[NH2:1][C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[CH:6][CH:5]=[CH:4][C:3]=1[C:12]([C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([OH:20])[CH:15]=1)=O.[CH:21](=O)[CH2:22][CH3:23]>>[CH3:23][C:22]1[CH:21]=[N:1][C:2]2[C:3]([C:12]=1[C:14]1[CH:15]=[C:16]([OH:20])[CH:17]=[CH:18][CH:19]=1)=[CH:4][CH:5]=[CH:6][C:7]=2[C:8]([F:11])([F:10])[F:9]

참가 물질

반응물 2

HCID 527Propanal

HCID 66586253[2-Amino-3-(trifluoromethyl)phenyl](3-hydroxyphenyl)methanone

생성물 1

HCID 665862653-[3-Methyl-8-(trifluoromethyl)quinolin-4-yl]phenol

실험 절차

The title compound was prepared from [2-amino-3-(trifluoromethyl)phenyl]-(3-hydroxy-phenyl)methanone and Propionaldehyde following the procedure of Example 457: MS (ES) m/z 304.28.

출처 및 근거

ORD 기록: ord-c0af89f7b7e44b798e54ec5eef61254c
출처 데이터셋: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07576215B2

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