Iodoethane → 3H-Indolium, 1-ethyl-5-methoxy-2,3,3-trimethyl-, iodide

HRID 2105100노트

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HRID 2105100 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([CH3:12])[C:6]2([CH3:14])[CH3:13].[I:15][CH2:16][CH3:17]>ClC1C=CC=CC=1Cl>[I-:15].[CH2:16]([N+:8]1[C:9]2[C:5](=[CH:4][C:3]([O:2][CH3:1])=[CH:11][CH:10]=2)[C:6]([CH3:14])([CH3:13])[C:7]=1[CH3:12])[CH3:17]

참가 물질

4

반응물 2

HCID 6340IodoethaneHCID 110953925-Methoxy-2,3,3-trimethyl-3H-indole

생성물 1

HCID 104276403H-Indolium, 1-ethyl-5-methoxy-2,3,3-trimethyl-, iodide

시약·촉매·용매 1

HCID 72391,2-Dichlorobenzene용매

반응 조건

온도
80 °C

실험 절차

To 5-methoxy-2,3,3-trimethyl-3H-indole (1.9 g) was added iodoethane (5 ml) and 1,2-dichlorobenzene (10 ml). The mixture was heated to 80° C. for 4 hours after which time the mixture was allowed to cool and the precipitate removed by filtration and washed sequentially with dichlorobenzene and diethyl ether. Drying in a vacuum oven gave the product (3 g).

후처리

  1. temperatureto cool
  2. customthe precipitate removed by filtration
  3. washwashed sequentially with dichlorobenzene and diethyl ether
  4. customDrying in a vacuum oven

출처 및 근거

ORD 기록
ord-04936a8e9a6f4d0ca0151ca74ceb186b
출처 데이터셋
uspto-grants-2009_08
특허 번호
US07579140B2

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