Triphenylphosphine → (tert-Butoxycarbonylmethyl)triphenylphosphonium Bromide

HRID 2106870

반응식

HRID 2106870 반응식
[C:1]1([P:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:20][CH2:21][C:22]([O:24][C:25]([CH3:28])([CH3:27])[CH3:26])=[O:23]>C1C=CC=CC=1>[Br-:20].[C:22]([CH2:21][P+:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)([O:24][C:25]([CH3:28])([CH3:27])[CH3:26])=[O:23]

참가 물질

4

반응물 2

HCID 11776TriphenylphosphineHCID 79177tert-Butyl bromoacetate

생성물 1

HCID 2733853(tert-Butoxycarbonylmethyl)triphenylphosphonium Bromide수율 96%

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

A solution of triphenylphosphine (33.8 g, 129 mmol) and t-butyl bromoacetate (25 g, 128.2 mmol) in dry benzene (150 ml) was stirred for 16 hours at room temperature. The precipitated product was collected by filtration, washed with dry ether and dried in vacuo to give 56 g (96% of theory) of carbo-t-butoxymethyl triphenylphosphonium bromide.

후처리

  1. filtrationThe precipitated product was collected by filtration
  2. washwashed with dry ether
  3. customdried in vacuo

출처 및 근거

ORD 기록
ord-f6b3f10780de4177b168c8ba64a75c9b
출처 데이터셋
uspto-grants-1990_06
특허 번호
US04931469

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