Acetic Anhydride → Ethyl 2-acetoxy-5-benzylideneaminobenzoate

HRID 2107015노트

반응식

HRID 2107015 반응식
[OH:1][C:2]1[CH:12]=[CH:11][C:10]([N:13]=[CH:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:9][C:3]=1[C:4]([O:6][CH2:7][CH3:8])=[O:5].[C:21](OC(=O)C)(=[O:23])[CH3:22]>N1C=CC=CC=1>[C:21]([O:1][C:2]1[CH:12]=[CH:11][C:10]([N:13]=[CH:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:9][C:3]=1[C:4]([O:6][CH2:7][CH3:8])=[O:5])(=[O:23])[CH3:22]

참가 물질

4

반응물 2

HCID 7918Acetic AnhydrideHCID 23047228Ethyl 2-hydroxy-5-benzylideneaminobenzoate

생성물 1

HCID 23047223Ethyl 2-acetoxy-5-benzylideneaminobenzoate수율 73%

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

Ethyl 2-hydroxy-5-benzylideneaminobenzoate (21 g, 78 mmole) was dissolved in pyridine (60 ml) and acetic anhydride (8.9 ml) was added after which the reaction mixture was kept at room temperature for 48 hours, evaporated to dryness in vacuo, and the residue recrystallized from hexane to give the title compound (17.8 g, 73%), m.p. 79°-80° C. Found (Calc. for C18H17NO4) C 69.33 (69.45), H 5.51 (5.47), N 4.57 (4.50).

후처리

  1. customevaporated to dryness in vacuo
  2. customthe residue recrystallized from hexane

출처 및 근거

ORD 기록
ord-e0729028dcb146fbaadc5cd8b27ca884
출처 데이터셋
uspto-grants-1990_06
특허 번호
US04933330

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