Triethylamine → HCID 15053525, 화합물

HRID 2107270노트

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HRID 2107270 반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9](=[O:20])[NH:10][C:11]2[S:12][CH:13]=[C:14](/[CH:16]=[CH:17]/[CH2:18][OH:19])[N:15]=2)=[CH:4][CH:3]=1.C(N(CC)CC)C>CS(C)=O>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9](=[O:20])[NH:10][C:11]2[S:12][CH:13]=[C:14](/[CH:16]=[CH:17]/[CH:18]=[O:19])[N:15]=2)=[CH:6][CH:7]=1

참가 물질

4

반응물 2

HCID 8471TriethylamineHCID 15053524HCID 15053524, 화합물

생성물 1

HCID 15053525HCID 15053525, 화합물

시약·촉매·용매 1

HCID 679Dimethyl Sulfoxide용매

실험 절차

Following a procedure similar to that described in Preparation 49, the desired compound was prepared from 0.84 g of (E)-3-[2-(3-p-bromophenylureido)thiazol-4-yl]allyl alcohol, 1.13 g of a sulfur trioxide pyridine complex, 0.72 g of triethylamine and 20 ml of dimethyl sulfoxide. The resulting product was a pale brown powder having the following physical properties.

후처리

  1. customthat described in Preparation 49

출처 및 근거

ORD 기록
ord-86ab7a0938d343aab6ae7e7b4b46efca
출처 데이터셋
uspto-grants-1990_06
특허 번호
US04933355

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