Triethylamine → 2-Ethylaminothiazole-4-carbaldehyde

HRID 2107280노트

반응식

HRID 2107280 반응식
[CH2:1]([NH:3][C:4]1[S:5][CH:6]=[C:7]([CH2:9][OH:10])[N:8]=1)[CH3:2].C(N(CC)CC)C>CS(C)=O>[CH2:1]([NH:3][C:4]1[S:5][CH:6]=[C:7]([CH:9]=[O:10])[N:8]=1)[CH3:2]

참가 물질

4

반응물 2

HCID 8471TriethylamineHCID 150535582-Ethylaminothiazol-4-ylmethanol

생성물 1

HCID 150535752-Ethylaminothiazole-4-carbaldehyde

시약·촉매·용매 1

HCID 679Dimethyl Sulfoxide용매

실험 절차

The reaction described in Preparation 44 was repeated, but using 4.4 g of 2-ethylaminothiazol-4-ylmethanol, 13.3 g of sulfur trioxide pyridine complex, 8.4 g of triethylamine and 60 ml of dimethyl sulfoxide, giving the title compound as pale brown prisms.

후처리

  1. customThe reaction described in Preparation 44

출처 및 근거

ORD 기록
ord-c98c479b5be64173be73c1ae950b16fb
출처 데이터셋
uspto-grants-1990_06
특허 번호
US04933355

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