Benzylamine → HCID 68872594, 화합물

반응식

[F:1][C:2]([F:15])([CH2:9][C:10]([O:12]CC)=O)[CH2:3][C:4]([O:6]CC)=O.[CH2:16]([NH2:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:16]([N:23]1[C:4](=[O:6])[CH2:3][C:2]([F:1])([F:15])[CH2:9][C:10]1=[O:12])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

참가 물질

반응물 2

HCID 7504Benzylamine

HCID 12696177Diethyl 3,3-difluoropentanedioate

생성물 1

HCID 68872594HCID 68872594, 화합물

실험 절차

React an 8.1 mmol portion of the product of Example 14 with benzylamine using the general procedure set forth in Example 8, and purify by silica gel chromatography using ethyl acetate/hexane as eluant to yield the title compound.

후처리

custompurify by silica gel chromatography

출처 및 근거

ORD 기록: ord-9b21c2ac84da40db9f19bae0bec19d6a
출처 데이터셋: uspto-grants-2009_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07514068B2

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