Benzyl Chloride → 2-Benzyl-3-(4-methylphenyl)-2H-indazole

HRID 2108998노트

반응식

HRID 2108998 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[NH:10][N:9]=2)=[CH:4][CH:3]=1.CC[O-].[Na+].[CH2:21](Cl)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH2:21]([N:9]1[C:8]([C:5]2[CH:4]=[CH:3][C:2]([CH3:1])=[CH:7][CH:6]=2)=[C:16]2[C:11]([CH:12]=[CH:13][CH:14]=[CH:15]2)=[N:10]1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

참가 물질

4

반응물 3

HCID 7503Benzyl ChlorideHCID 2723922Sodium ethoxideHCID 98777323-(4-methylphenyl)-1H-indazole

생성물 1

HCID 115222532-Benzyl-3-(4-methylphenyl)-2H-indazole수율 5%

실험 절차

Compound 10 (6.24 g, 0.03 mol), EtONa (4.08 g, 0.06 mol) and benzyl chloride (10.18 g, 0.08 mol) were allowed to react as in the preparation of compound 15 to afford compound 26 (0.45 g, 5%).

출처 및 근거

ORD 기록
ord-6e4388aeb2994944ba8f9396f2042b5f
출처 데이터셋
uspto-grants-2009_04
특허 번호
US07514465B2

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