N-(3-Fluorophenyl)-6-nitropyridin-3-amine → HCID 28477225, 화합물

HRID 2110992노트

반응식

HRID 2110992 반응식
[F:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]2[CH:10]=[N:11][C:12]([N+:15]([O-])=O)=[CH:13][CH:14]=2)[CH:5]=[CH:6][CH:7]=1>[Ni].CO>[F:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([NH2:15])=[N:11][CH:10]=2)[CH:5]=[CH:6][CH:7]=1

참가 물질

4

반응물 1

HCID 57636791N-(3-Fluorophenyl)-6-nitropyridin-3-amine

생성물 1

HCID 28477225HCID 28477225, 화합물수율 98.4%

시약·촉매·용매 2

HCID 935Nickel촉매HCID 887Methanol용매

실험 절차

This compound was easily prepared from N-(3-fluorophenyl)-6-nitro-3-pyridinamine 210 mg, 0.9 mmol) by catalytic hydrogenation (Raney nickel at atmospheric pressure) in methanol to give the desired product (180 mg, 98%)

출처 및 근거

ORD 기록
ord-394ad5acd5af44be9d8edd28a851fb3f
출처 데이터셋
uspto-grants-2009_04
특허 번호
US07517992B2

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