4-Fluoroaniline → N-(4-fluorophenyl)-2-(3-methoxyphenyl)acetamide

HRID 2114693노트

반응식

HRID 2114693 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:9][C:10](Cl)=[O:11])[CH:6]=[CH:7][CH:8]=1.[F:13][C:14]1[CH:20]=[CH:19][C:17]([NH2:18])=[CH:16][CH:15]=1>>[F:13][C:14]1[CH:20]=[CH:19][C:17]([NH:18][C:10](=[O:11])[CH2:9][C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=2)=[CH:16][CH:15]=1

참가 물질

3

반응물 2

HCID 97314-FluoroanilineHCID 27332463-Methoxyphenylacetyl chloride

생성물 1

HCID 2704885N-(4-fluorophenyl)-2-(3-methoxyphenyl)acetamide수율 98%

실험 절차

The title compound was prepared as described in Example 1.A, using 3-methoxyphenylacetyl chloride (3.29 g, 18.0 mmol) and 4-fluoroaniline (1.98 g, 18.0 mmol) to afford the title compound (4.57 g, 98% yield): ES-MS (m/z) 259.

후처리

  1. customThe title compound was prepared

출처 및 근거

ORD 기록
ord-03a0986e41804dbb9d70527ba3a058eb
출처 데이터셋
uspto-grants-2008_10
특허 번호
US07435729B2

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