5-Amino-2-oxindole → HCID 69100718, 화합물

HRID 2114982

반응식

HRID 2114982 반응식
[O:1]=[C:2]([N:6]1[CH2:11][CH2:10][CH:9]([O:12][C:13]2[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][CH:14]=2)[CH2:8][CH2:7]1)[C:3]([OH:5])=O.[NH2:20][C:21]1[CH:22]=[C:23]2[C:27](=[CH:28][CH:29]=1)[NH:26][C:25](=[O:30])[CH2:24]2>>[O:1]=[C:2]([N:6]1[CH2:11][CH2:10][CH:9]([O:12][C:13]2[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][CH:14]=2)[CH2:8][CH2:7]1)[C:3]([NH:20][C:21]1[CH:22]=[C:23]2[C:27](=[CH:28][CH:29]=1)[NH:26][C:25](=[O:30])[CH2:24]2)=[O:5]

참가 물질

3

반응물 2

HCID 27732135-Amino-2-oxindoleHCID 69100252Oxo-(4-p-tolyloxy-piperidin-1-yl)-acetic acid

생성물 1

HCID 69100718HCID 69100718, 화합물

실험 절차

The title compound is prepared from oxo-(4-p-tolyloxy-piperidin-1-yl)-acetic acid and 5-amino-1,3-dihydro-indol-2-one according to the method described in Example 2. The filtered crystals are purified by column chromatography using Kieselgel 60 (Merck) as adsorbent and toluene:methanol=4:1 as eluent. Melting Point: 176-178° C. (diethyl ether)

후처리

  1. customThe filtered crystals are purified by column chromatography

출처 및 근거

ORD 기록
ord-52765ca6e0a44ddea76137d35145b8fb
출처 데이터셋
uspto-grants-2008_10
특허 번호
US07435744B2

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