Potassium Iodide → 1-Methyl-5-nitroquinolin-1-ium iodide

HRID 2117319노트

반응식

HRID 2117319 반응식
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][CH:8]=[N:9]2)([O-:3])=[O:2].S(OC)(O[CH3:18])(=O)=O.[I-:21].[K+]>O>[I-:21].[CH3:18][N+:9]1[C:10]2[C:5](=[C:4]([N+:1]([O-:3])=[O:2])[CH:13]=[CH:12][CH:11]=2)[CH:6]=[CH:7][CH:8]=1

참가 물질

5

반응물 3

HCID 4875Potassium IodideHCID 6497Dimethyl SulfateHCID 118295-Nitroquinoline

생성물 1

HCID 124950501-Methyl-5-nitroquinolin-1-ium iodide

시약·촉매·용매 1

HCID 962Water용매

실험 절차

5-Nitroquinoline (4 g, 30 mmol) was melted at 85° C., prior to addition of dimethyl sulfate (2.2 ml, 30 mmol), and the resulting mixture was stirred at this temperature for 1.5 hours. The yellow gel was dissolved in water (35 ml) and cooled to room temperature. A saturated aqueous solution of potassium iodide (7.63 g, 45.9 mmol) was added, and the resulting orange precipitate was filtered, washing the residue with chilled water. After drying under vacuum at 60° C., for 2 hours, the brick-red solid was used in the next step without purification.

후처리

  1. filtrationthe resulting orange precipitate was filtered
  2. washwashing the residue with chilled water
  3. customAfter drying under vacuum at 60° C., for 2 hours
  4. customthe brick-red solid was used in the next step without purification

출처 및 근거

ORD 기록
ord-ec8fbf85c3ab4e498eea5f7341e343fd
출처 데이터셋
uspto-grants-2008_10
특허 번호
US07442701B2

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