Diazomethane → 2,4,5-Trimethylisoxazol-3(2H)-one
반응식
[OH:1][C:2]1[C:6]([CH3:7])=[C:5]([CH3:8])[O:4][N:3]=1.[N+](=[CH2:11])=[N-]>CCOCC>[CH3:11][N:3]1[C:2](=[O:1])[C:6]([CH3:7])=[C:5]([CH3:8])[O:4]1참가 물질
4
실험 절차
To a solution of 3-hydroxy-4,5-dimethylisoxazole (7 g, 62 mmol) in ether (50 mL) was added diazomethane until a persistent yellow colour was obtained. The reaction was stirred for another 30 min at room temperature. The ether was evaporated off and the residue purified by column chromatography on silica gel using ether as eluent. 4 g of the desired material was obtained.
후처리
- customwas obtained
- customThe ether was evaporated off
- customthe residue purified by column chromatography on silica gel
출처 및 근거
- ORD 기록
- ord-106c5a73609441c0bb0ac152402a1ea8
- 출처 데이터셋
- uspto-grants-2004_02
- 특허 번호
- US06693111B1
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