1-Acetylnaphthalene → 1-(Naphthalen-1-yl)ethanone oxime

HRID 2122100

반응식

HRID 2122100 반응식
[C:1]([C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=[CH:6][CH:5]=1)(=O)[CH3:2].Cl.[NH2:15][OH:16]>N1C=CC=CC=1>[C:1](=[N:15][OH:16])([C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=[CH:6][CH:5]=1)[CH3:2]

참가 물질

4

반응물 2

HCID 136631-AcetylnaphthaleneHCID 443297Hydroxyamine hydrochloride

생성물 1

HCID 3496811-(Naphthalen-1-yl)ethanone oxime수율 65%

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

In a 50 ml round-bottom flask, a mixture of acetonaphthone, hydroxylamine hydrochloride in pyridine was stirred, at room temperature under nitrogen blanket, for five days. The reaction mixture was then concentrated under vacuum to remove most of pyridine. The oil was then dissolved in dichloromethane. The product precipitated on standing. The product was obtained as a white solid in 65% yield.

후처리

  1. concentrationThe reaction mixture was then concentrated under vacuum
  2. customto remove most of pyridine
  3. dissolutionThe oil was then dissolved in dichloromethane
  4. customThe product precipitated
  5. customThe product was obtained as a white solid in 65% yield

출처 및 근거

ORD 기록
ord-c499d1520b644d4698af39ebe86f5379
출처 데이터셋
uspto-grants-2004_02
특허 번호
US06696608B1

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