Dichloromethane → tert-butyl (3RS,4RS)-3-hydroxy-4-(4-trityloxymethyl-phenyl)-piperidine-1-carboxylate

반응식

[CH2:50]([Cl:51])[Cl:52].[CH3:43][CH2:44][N:45]([CH2:46][CH3:47])[CH2:48][CH3:49].[OH:1][CH:2]1[CH2:3][N:4]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([CH2:14][OH:15])[cH:12][cH:13]1.[c:23]1([C:29]([Cl:30])([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:24][cH:25][cH:26][cH:27][cH:28]1>>[OH:1][CH:2]1[CH2:3][N:4]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([CH2:14][O:15][C:29]([c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:12][cH:13]1