Dichloromethane → tert-butyl N-[3-cyclohexyl-2-[[3-[(3-fluorophenyl)-[2-(methoxycarbonylamino)ethoxy]methyl]piperidine-1-carbonyl]amino]propyl]-N-methylcarbamate
반응식
[C:20](=[O:21])([n:22]1[cH:23][cH:24][n:25][cH:26]1)[n:27]1[cH:28][cH:29][n:30][cH:31]1.[CH:32]([N:33]([CH2:34][CH3:35])[CH:36]([CH3:37])[CH3:38])([CH3:39])[CH3:40].[Cl:63][CH2:64][Cl:65].[F:41][c:42]1[cH:43][c:44]([CH:48]([O:49][CH2:50][CH2:51][NH:52][C:53]([O:54][CH3:55])=[O:56])[CH:57]2[CH2:58][NH:59][CH2:60][CH2:61][CH2:62]2)[cH:45][cH:46][cH:47]1.[NH2:1][CH:2]([CH2:3][N:4]([C:5]([O:6][C:7]([CH3:8])([CH3:9])[CH3:10])=[O:11])[CH3:12])[CH2:13][CH:14]1[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1>>[NH:1]([CH:2]([CH2:3][N:4]([C:5]([O:6][C:7]([CH3:8])([CH3:9])[CH3:10])=[O:11])[CH3:12])[CH2:13][CH:14]1[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1)[C:20](=[O:21])[N:59]1[CH2:58][CH:57]([CH:48]([c:44]2[cH:43][c:42]([F:41])[cH:47][cH:46][cH:45]2)[O:49][CH2:50][CH2:51][NH:52][C:53]([O:54][CH3:55])=[O:56])[CH2:62][CH2:61][CH2:60]1
