Hydrochloric Acid → (5-(R)-(4-aminomethylphenyl)-2,4-dioxoimidazolidin-3-yl)acetic acid hydrochloride

HRID 21499노트

반응식

HRID 21499 반응식
C(OC([NH:11][CH2:12][C:13]1[CH:18]=[CH:17][C:16]([C@@H:19]([NH:24][C:25]([NH:27][CH2:28][C:29]([O:31]CC)=[O:30])=[O:26])[C:20](OC)=[O:21])=[CH:15][CH:14]=1)=O)C1C=CC=CC=1.[ClH:34]>>[ClH:34].[NH2:11][CH2:12][C:13]1[CH:18]=[CH:17][C:16]([C@H:19]2[NH:24][C:25](=[O:26])[N:27]([CH2:28][C:29]([OH:31])=[O:30])[C:20]2=[O:21])=[CH:15][CH:14]=1

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 67799367HCID 67799367, 화합물

생성물 1

HCID 67798814(5-(R)-(4-aminomethylphenyl)-2,4-dioxoimidazolidin-3-yl)acetic acid hydrochloride

실험 절차

280 mg of N-(1-(R)-(4-benzyloxycarbonylaminomethylphenyl-1-methoxycarbonylmethyl),N'-ethoxycarbonylmethylurea are boiled under reflux for 45 min in 4 ml of 6N HCl and the mixture is then concentrated and dried over KOH.

후처리

  1. concentrationthe mixture is then concentrated
  2. dry with materialdried over KOH

출처 및 근거

ORD 기록
ord-5768d5e45d17463e94180f69eeb44af0
출처 데이터셋
uspto-grants-1995_06
특허 번호
US05424293

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