Dichloromethane → tert-butyl 4-fluoro-2-[[1-(4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]carbamoyl]pyrrolidine-1-carboxylate

HRID 2150250노트

반응식

[C:31]([CH3:32])([CH3:33])([CH3:34])[O:35][C:36](=[O:37])[N:38]1[CH:39]([C:44](=[O:45])[OH:46])[CH2:40][CH:41]([F:43])[CH2:42]1.[CH3:47][CH2:48][N:49]=[C:50]=[N:51][CH2:52][CH2:53][CH2:54][N:55]([CH3:56])[CH3:57].[CH3:61][N:62]([c:63]1[cH:64][cH:65][n:66][cH:67][cH:68]1)[CH3:69].[Cl:58][CH2:59][Cl:60].[F:1][c:2]1[cH:3][c:4]([C:15]([CH2:16][c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)([NH2:23])[c:24]2[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]2)[cH:5][c:6]([O:8][C:9]([CH:10]([F:11])[F:12])([F:13])[F:14])[cH:7]1>>[F:1][c:2]1[cH:3][c:4]([C:15]([CH2:16][c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)([NH:23][C:44]([CH:39]2[N:38]([C:36]([O:35][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:37])[CH2:42][CH:41]([F:43])[CH2:40]2)=[O:45])[c:24]2[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]2)[cH:5][c:6]([O:8][C:9]([CH:10]([F:11])[F:12])([F:13])[F:14])[cH:7]1