Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
m-Chloroperbenzoic acid → N-(3-chloro-phenyl)-4-(N-oxido4-pyridyl)-2-pyrimidineamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | m-Chloroperbenzoic acid | HCID 70297 | — |
| 반응물 | 2-pyrimidinamine, N-(3-chlorophenyl)-4-(4-pyridinyl)- | HCID 644214 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-(3-chloro-phenyl)-4-(N-oxido4-pyridyl)-2-pyrimidineamine | HCID 19689585 | — |
반응 단계
10 g (35.4 mmol) of N-(3-chloro-phenyl)-4-(4-pyridyl)-2-pyrimidineamine and 11.1 g (35.4 mmol) of m-chloroperbenzoic acid are stirred for 5 h at RT in 500 ml of methylene chloride. Concentration and crystallisation (acetic acid) of the residue give N-(3-chloro-phenyl)-4-(N-oxido4-pyridyl)-2-pyrimidineamine; m.p. 274°-275°, Rf =0.6 (methylene chloride:methanol=9:1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05728708 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-a39fc3b67bbd45ff88d29b84e47f577f |
| 출처 메모 | uspto-grants-1998_03 |