HRID2158

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID70297

Benzenecarboperoxoic acid, 3-chloro-

C7H5ClO3

HCID644214

2-pyrimidinamine, N-(3-chlorophenyl)-4-(4-pyridinyl)-

C15H11ClN4

PRODUCTS

生成物

结构：[O-][n+]1ccc(-c2ccnc(Nc3cccc(Cl)c3)n2)cc1

HCID19689585

N-(3-Chlorophenyl)-4-(1-oxido-4-pyridinyl)-2-pyrimidinamine

C15H11ClN4O

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

10 g (35.4 mmol) of N-(3-chloro-phenyl)-4-(4-pyridyl)-2-pyrimidineamine and 11.1 g (35.4 mmol) of m-chloroperbenzoic acid are stirred for 5 h at RT in 500 ml of methylene chloride. Concentration and crystallisation (acetic acid) of the residue give N-(3-chloro-phenyl)-4-(N-oxido4-pyridyl)-2-pyrimidineamine; m.p. 274°-275°, Rf =0.6 (methylene chloride:methanol=9:1).

WORKUP

后处理

concentrationConcentration and crystallisation (acetic acid) of the residue