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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 215870생성일: 2026년 10월 25일

(R)-(+)-1-Boc-3-aminopyrrolidine → (R)-3-Amino-pyrrolidine-1-carboxylic acid (R)-pyrrolidin-3-ylamide

https://huagongshe.com/reaction/215870

반응식

참여 물질

역할이름HCID투입량
반응물(R)-(+)-1-Boc-3-aminopyrrolidineHCID 854070—
반응물(R)-3-Amino-pyrrolidine-1-carboxylic acid (4-amino-cyclohexyl)-amideHCID 67022910—
생성물(R)-3-Amino-pyrrolidine-1-carboxylic acid (R)-pyrrolidin-3-ylamideHCID 58025012—

반응 단계

(R)-3-Amino-pyrrolidine-1-carboxylic acid (R)-pyrrolidin-3-ylamide is prepared analogously to (R)-3-amino-pyrrolidine-1-carboxylic acid (4-amino-cyclohexyl)-amide (Intermediate IF) by replacing (4-amino-cyclohexyl)-carbamic acid tert-butyl ester with (R)-3-amino-pyrrolidine-1-carboxylic acid tert-butyl ester.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08193164B2
출처 데이터셋uspto-grants-2012_06
ORD IDord-983da489732248f1890945b0fd8bd093
출처 메모uspto-grants-2012_06