Toluene → 4-[5-(2-Methylthiopyrimidin-4-yl)-1-methyl-4-(3-trifluoromethylphenyl)-1H-imidazol-2-yl]-piperidine-1-carboxylic acid benzyl ester

반응식

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][CH:14]([c:17]2[nH:18][c:19](-[c:32]3[n:33][c:34]([S:38][CH3:39])[n:35][cH:36][cH:37]3)[c:20](-[c:22]3[cH:23][c:24]([C:28]([F:29])([F:30])[F:31])[cH:25][cH:26][cH:27]3)[n:21]2)[CH2:15][CH2:16]1.[CH3:40][O:41][CH:42]([O:43][CH3:44])[N:45]([CH3:46])[CH3:47].[CH3:48][c:49]1[cH:50][cH:51][cH:52][cH:53][cH:54]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][CH:14]([c:17]2[n:18]([CH3:40])[c:19](-[c:32]3[n:33][c:34]([S:38][CH3:39])[n:35][cH:36][cH:37]3)[c:20](-[c:22]3[cH:23][c:24]([C:28]([F:29])([F:30])[F:31])[cH:25][cH:26][cH:27]3)[n:21]2)[CH2:15][CH2:16]1