Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyanoacetamide → alpha-Cyano-beta-(2-Nitro-4,5-Dimethoxyphenyl)Acrylamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyanoacetamide | HCID 7898 | — |
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | 6-Nitroveratraldehyde | HCID 88505 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | alpha-Cyano-beta-(2-Nitro-4,5-Dimethoxyphenyl)Acrylamide | HCID 4145653 | — |
반응 단계
Piperidine (2.1 g., 0.0237mole) and 2-cyanoacetamide (22.0g., 0.263 mole) are added to a slurry of 6-nitroveratraldehyde (50.0 g., 0.237 mole) in methanol (500 ml.). The mixture is heated to reflux for two hours, and then cooled in an ice bath and filtered. The bright yellow filter cake is washed with cold isopropanol (300 ml.) and then air dried. Yield = 60.1 g. (93%); m.p. 265°-266° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04134981 |
| 출처 데이터셋 | uspto-grants-1979_01 |
| ORD ID | ord-2e88bbac5f924a2cb8269c8b139714cc |
| 출처 메모 | uspto-grants-1979_01 |