Ethylenediamine → HCID 12632114, 화합물

HRID 2163674노트

반응식

HRID 2163674 반응식
[C:1]1([C:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)([CH3:10])C#N)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:17]([NH2:20])[CH2:18][NH2:19].S([C:25]1C=CC(C)=CC=1)([O-])(=O)=O>>[C:11]1([CH:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[CH2:10][C:25]2[NH:19][CH2:18][CH2:17][N:20]=2)[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1

참가 물질

4

반응물 3

HCID 3301EthylenediamineHCID 796772,2-DiphenylpropiononitrileHCID 85570p-Toluenesulfonate

생성물 1

HCID 12632114HCID 12632114, 화합물

실험 절차

A mixture of 2.07 g of 2,2-diphenyl propionitrile and 2.78 g of ethylenediamine.tosylate was heated at 200° C. for 3 hours. After cooling, the solution was rendered basic with an alkali hydroxide and extracted with chloroform. The chloroform layer was washed with water and dried. After evaporating chloroform, the resulting residue was recrystallized from a mixture of benzene and hexane to give 1.4 g of 2-(2,2-diphenyl ethyl)-2-imidazoline having a melting point of 98° to 101° C. The hydrochloride thereof had a melting point of 173°-175° C.

후처리

  1. temperatureAfter cooling
  2. extractionextracted with chloroform
  3. washThe chloroform layer was washed with water
  4. customdried
  5. customAfter evaporating chloroform
  6. customthe resulting residue was recrystallized from a mixture of benzene and hexane

출처 및 근거

ORD 기록
ord-46bc966e1cd8498b964d04d53e130357
출처 데이터셋
uspto-grants-1979_01
특허 번호
US04136188

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