Ethyl formate → HCID 22751278, 화합물
반응식
[C:1]1([CH:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH2:8][C:9]2[NH:10][CH2:11][CH2:12][N:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:20]([O:22]C=O)C>>[CH:20]([N:13]1[CH2:12][CH2:11][N:10]=[C:9]1[CH2:8][CH:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)=[O:22]참가 물질
3
실험 절차
a mixture of 2.5 g of 2-(2,2-diphenyl ethyl)-2-imidazoline and 50 ml of ethylformate was refluxed for 5 hours. After the reaction, unreacted ethylformate was removed by distillation. The resulting residue was subjected to silica gel column chromatography and eluted with methylene chloride. The solvent was removed by distillation from the eluate to give 1.2 g of 1-formyl-2-(2,2-diphenyl ethyl)-2-imidazoline having a melting point of 105° to 107° C.
후처리
- temperaturewas refluxed for 5 hours
- customwas removed by distillation
- washeluted with methylene chloride
- customThe solvent was removed by distillation from the eluate