Diisopropylethylamine → 6-(4-Bromo-2-methyl-phenylamino)-7-fluoro-3-pent-4-enyl-3H-benzoimidazole-5-carboxylic acid cyclopropylmethoxy-amide

반응식

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]2[C:10]([C:24]([OH:26])=O)=[CH:11][C:12]3[N:16]([CH2:17][CH2:18][CH2:19][CH:20]=[CH2:21])[CH:15]=[N:14][C:13]=3[C:22]=2[F:23])=[C:4]([CH3:27])[CH:3]=1.CCN(C(C)C)C(C)C.C1CN([P+](ON2N=NC3C=[CH:58][CH:59]=[CH:60][C:55]2=3)(N2CCCC2)N2CCCC2)CC1.F[P-](F)(F)(F)(F)F.Cl.C1([N:74](C)[OH:75])CC1>C1COCC1.C(Cl)Cl.C(OCC)(=O)C>[CH:59]1([CH2:58][O:75][NH:74][C:24]([C:10]2[C:9]([NH:8][C:5]3[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][C:4]=3[CH3:27])=[C:22]([F:23])[C:13]3[N:14]=[CH:15][N:16]([CH2:17][CH2:18][CH2:19][CH:20]=[CH2:21])[C:12]=3[CH:11]=2)=[O:26])[CH2:60][CH2:55]1