HCID 23044549, 화합물 → HCID 131716457, 화합물

반응식

[Cl:1][CH2:2][CH:3]1[O:7]C=[N:5][CH:4]1[C:8]([NH2:10])=[O:9]>Cl>[ClH:1].[Cl:1][CH2:2][CH:3]([OH:7])[CH:4]([C:8]([NH2:10])=[O:9])[NH2:5]

참가 물질

반응 조건

온도: 50 °C

실험 절차

5-(Chloromethyl)-4,5-dihydro-4-oxazolecarboxamide was dissolved in 1500 ml of 2N hydrochloric acid and warmed to 50° C. for 2 hours. The hydrochloric acid was removed in vacuo and the residue was triturated with isopropanol to yield the title compound as brownish crystals; yield 133.9 g.

후처리

customThe hydrochloric acid was removed in vacuo
customthe residue was triturated with isopropanol

출처 및 근거

ORD 기록: ord-95f3abde35e6494890f64eef7719b935
출처 데이터셋: uspto-grants-1990_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04939253

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참가 물질

반응물 1

HCID 23044549HCID 23044549, 화합물

생성물 1

HCID 131716457HCID 131716457, 화합물

시약·촉매·용매 1

HCID 313Hydrochloric Acid용매

반응 조건

온도: 50 °C

실험 절차

후처리

customThe hydrochloric acid was removed in vacuo
customthe residue was triturated with isopropanol

출처 및 근거

ORD 기록: ord-95f3abde35e6494890f64eef7719b935
출처 데이터셋: uspto-grants-1990_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04939253

반응 노트

불러오는 중…