Tetrahydrofuran → N'-(3-Bromophenyl)-N,N-dibutylurea
반응식
[Br:1][C:2]1[CH:3]=[C:4]([NH:8][C:9](=[O:11])[O-])[CH:5]=[CH:6][CH:7]=1.O1CCCC1.[CH2:17]([NH:21][CH2:22][CH2:23][CH2:24][CH3:25])[CH2:18][CH2:19][CH3:20]>CCCCCC>[CH2:17]([N:21]([CH2:22][CH2:23][CH2:24][CH3:25])[C:9]([NH:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([Br:1])[CH:3]=1)=[O:11])[CH2:18][CH2:19][CH3:20]참가 물질
5
실험 절차
A solution of 1.46 g. of phenyl N-(3-bromophenylcarbamate in 15 ml. of tetrahydrofuran is added to a solution of 1.52 g. of di-n-butylamine in 20 ml. of tetrahydrofuran and the mixture is stirred under reflux for 24 hours. The mixture is diluted with hexane and the precipitate collected by filtration. Recrystallization from pentane affords 1,1-di-(n-butyl)-3-(3-bromophenyl)urea, m.p. 80°-81° C.
후처리
- temperatureunder reflux for 24 hours
- filtrationthe precipitate collected by filtration
- customRecrystallization from pentane
출처 및 근거
- ORD 기록
- ord-f73b2f0f28c641d4ba2658f41d63b3d7
- 출처 데이터셋
- uspto-grants-1983_06
- 특허 번호
- US04387105
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