Hydrochloric Acid → HCID 66672546, 화합물

HRID 2167783노트

반응식

HRID 2167783 반응식
[ClH:1].[CH3:2][S:3]([N:6]1[CH2:10][CH2:9][C@H:8]([NH:11]C(=O)OC(C)(C)C)[CH2:7]1)(=[O:5])=[O:4]>>[ClH:1].[CH3:2][S:3]([N:6]1[CH2:10][CH2:9][C@H:8]([NH2:11])[CH2:7]1)(=[O:5])=[O:4]

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 58959879(S)-tert-butyl (1-(methylsulfonyl)pyrrolidin-3-yl)carbamate

생성물 1

HCID 66672546HCID 66672546, 화합물

실험 절차

4M HCl solution (in Dioxane) (2 mL) and (S)-tert-butyl (1-(methylsulfonyl)pyrrolidin-3-yl)carbamate (200 mg, 0.99 mmol) was stirred at 20-35° C. for 2 h. The solid precipitate thus obtained was filtered, washed with hexane and dried to afford 120 mg of the title compound.

후처리

  1. customThe solid precipitate thus obtained
  2. filtrationwas filtered
  3. washwashed with hexane
  4. customdried

출처 및 근거

ORD 기록
ord-97ea739a9be6439b807611b19984e593
출처 데이터셋
uspto-grants-2015_06
특허 번호
US09045479B2

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