Sodium borohydride → [1-(4-Bromophenyl)cyclopentyl]methanol

HRID 2169268노트

반응식

HRID 2169268 반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([CH:13]=[O:14])[CH2:12][CH2:11][CH2:10][CH2:9]2)=[CH:4][CH:3]=1.[BH4-].[Na+]>CO>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2([CH2:13][OH:14])[CH2:12][CH2:11][CH2:10][CH2:9]2)=[CH:6][CH:7]=1

참가 물질

4

반응물 2

HCID 4311764Sodium borohydrideHCID 225029301-(4-Bromophenyl)-cyclopentanecarbaldehyde

생성물 1

HCID 67480063[1-(4-Bromophenyl)cyclopentyl]methanol

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

To a stirred solution of 1-(4-bromophenyl)-cyclopentanecarbaldehyde (225) (51.0 g, 201.47 mmol) in methanol (400 mL), was added NaBH4 (15.31 g, 402.94 mmol) portion-wise at 0° C.

출처 및 근거

ORD 기록
ord-0a963ea57c0f4f548b7b1b67435917ea
출처 데이터셋
uspto-grants-2015_06
특허 번호
US09045486B2

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