Ibuprofen, (+-)- → HCID 15948295, 화합물

HRID 2170008노트

반응식

HRID 2170008 반응식
[OH:1][C:2]([CH:4]([C:6]1[CH:15]=[CH:14][C:9]([CH2:10][CH:11]([CH3:13])[CH3:12])=[CH:8][CH:7]=1)[CH3:5])=[O:3].[OH-].[Na+].O.O.O.O.O.O.[Cl-].[Sr+2:25].[Cl-]>O>[O-:3][C:2]([CH:4]([C:6]1[CH:7]=[CH:8][C:9]([CH2:10][CH:11]([CH3:12])[CH3:13])=[CH:14][CH:15]=1)[CH3:5])=[O:1].[Sr+2:25].[O-:3][C:2]([CH:4]([C:6]1[CH:7]=[CH:8][C:9]([CH2:10][CH:11]([CH3:12])[CH3:13])=[CH:14][CH:15]=1)[CH3:5])=[O:1]

참가 물질

5

반응물 3

HCID 3672Ibuprofen, (+-)-HCID 14798Sodium HydroxideHCID 6101868Strontium chloride hexahydrate

생성물 1

HCID 15948295HCID 15948295, 화합물

시약·촉매·용매 1

HCID 962Water용매2회

실험 절차

Ibuprofen (2.59 g, 12.5 mmol) was dissolved in water (100 ml) containing sodium hydroxide (0.503 g, 12.5 mmol). A solution of strontium chloride hexahydrate (1.68 g, 6.3 mmol) in water (5 ml) was added. The mixture was stirred for 10 minutes at room temperature and the title compound was isolated by filtration and dried. Yield 1.30 g (44%). Melting point>300.degree. C.

출처 및 근거

ORD 기록
ord-27849d9ff56a4ceb92c3ad2c871b5646
출처 데이터셋
uspto-grants-2015_06
특허 번호
US09050312B2

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