3-Cyanopyridine → 3-Pyridinemethanamine

HRID 21702

반응식

HRID 21702 반응식
[CH3:1][NH:2][CH2:3][C:4]1[CH:5]=[N:6][CH:7]=[CH:8][CH:9]=1.[C:10]([C:12]1[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=1)#[N:11].CN>[Ni]>[CH3:1][NH:2][CH2:3][C:4]1[CH:5]=[N:6][CH:7]=[CH:8][CH:9]=1.[N:14]1[CH:15]=[CH:16][CH:17]=[C:12]([CH2:10][NH2:11])[CH:13]=1

참가 물질

6

반응물 3

HCID 793-CyanopyridineHCID 6329MethylamineHCID 883933-(Methylaminomethyl)pyridine

생성물 2

HCID 310183-PyridinemethanamineHCID 883933-(Methylaminomethyl)pyridine

시약·촉매·용매 1

HCID 935Nickel촉매

실험 절차

For example, in U.S. Pat. No. 2,798,077, "Preparation of Methyl-(beta-picolyl)-Amine," issued to R. Schlapfer et al. in 1957, it is disclosed that 3-cyanopyridine can be hydrogenated h the presence of excess methylamine and a Raney nickel catalyst to yield N-methyl-3-picolylamine and beta-picolylamine. Separation of the beta-picolylamine is then required.

출처 및 근거

ORD 기록
ord-6ee07b756e3b4081a7d4d3e7fe09730e
출처 데이터셋
uspto-grants-1995_06
특허 번호
US05424436

연결된 노트

불러오는 중…