(R)-2-amino-3-(4-ethoxy-phenyl)-propionic acid hydrochloride → O-Ethyl-D-tyrosine

HRID 2170252노트

반응식

HRID 2170252 반응식
C(OC([NH:8][C@H:9]([CH2:13][C:14]1[CH:19]=[CH:18][C:17]([O:20][CH2:21][CH3:22])=[CH:16][CH:15]=1)[C:10]([OH:12])=[O:11])=O)CCC.Cl.N[C@H](CC1C=CC(OCC)=CC=1)C(O)=O>Cl.O1CCOCC1>[NH2:8][C@H:9]([CH2:13][C:14]1[CH:15]=[CH:16][C:17]([O:20][CH2:21][CH3:22])=[CH:18][CH:19]=1)[C:10]([OH:12])=[O:11]

참가 물질

5

반응물 2

HCID 71185515(R)-2-amino-3-(4-ethoxy-phenyl)-propionic acid hydrochlorideHCID 71186057(R)-2-Butoxycarbonylamino-3-(4-ethoxy-phenyl)-propionic acid

생성물 1

HCID 18596379O-Ethyl-D-tyrosine

시약·촉매·용매 2

HCID 313Hydrochloric Acid용매HCID 312751,4-Dioxane용매

실험 절차

(R)-2-Butoxycarbonylamino-3-(4-ethoxy-phenyl)-propionic acid (4.0 g, 12.93 mmol) was dissolved in 4M HCl in dioxan (150 mL). After one hour at room temperature the solvent was removed in vacuo to give a white solid identified as (R)-2-amino-3-(4-ethoxy-phenyl)-propionic acid hydrochloride (3.18 g, 12.9 mmol, 100%).

후처리

  1. customAfter one hour at room temperature the solvent was removed in vacuo
  2. customto give a white solid

출처 및 근거

ORD 기록
ord-79e56e508643468184df324f8404c064
출처 데이터셋
uspto-grants-2015_06
특허 번호
US09051249B2

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