3-Cyanopyridine → N-(pyridin-3-ylmethyl)aniline
반응식
[C:1]([C:3]1[CH:4]=[N:5][CH:6]=[CH:7][CH:8]=1)#[N:2].N[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.[H][H]>[Rh]>[C:10]1([NH:2][CH2:1][C:3]2[CH:4]=[N:5][CH:6]=[CH:7][CH:8]=2)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1참가 물질
5
실험 절차
A mixture of 3-cyanopyridine (10.4 g), aniline (101.8 g) and a 5% rhodium on carbon catalyst (1.0 g) was treated with hydrogen at 60 psig 30 deg C. for 13 hours in a rocking autoclave. The catalyst was removed by filtration and the filtrate analyzed by glc to show 3.7 g of N-phenyl-N-(3-pyridylmethyl)amine.
후처리
- customThe catalyst was removed by filtration
출처 및 근거
- ORD 기록
- ord-2dc1b1df31414fdabba8d25b8bcdf139
- 출처 데이터셋
- uspto-grants-1995_06
- 특허 번호
- US05424436
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